Modelling in hypertension: gaps, challenges, and future directions

New article published in PharmacoEconomics, co-authored by HEOR: 

A systematic literature review of health economic modelling approaches used to evaluate treatment-resistant and uncontrolled hypertension: a critical appraisal and considerations for the design of future model analyses

Patrice Carter, Principal Consultant, and Geraint Roberts, Senior Medical Writer, summarise HEOR’s contribution:  

Our systematic literature review aimed to critically assess the construct validity and quality of existing health economic models used to evaluate management approaches for uncontrolled and treatment-resistant hypertension. Identified models demonstrated that improvements in blood pressure were cost-effective; however, inputs based on non- and general- hypertensive populations likely underestimate the risk of cardiovascular events in people with uncontrolled or treatment-resistant hypertension. Furthermore, despite the potential economic burden, no models were identified which evaluated emerging pharmacotherapies in these underserved populations.