Total System Value™


Total System Value™ (TSV)™ is a new, dynamic framework designed to assess the value of adopting a new technology or policy initiative at a population level. It demonstrates how various parts of the healthcare system are impacted by tracking disease progression over time in the context of the management of the disease and the changing profile of the population.

Value within healthcare may be defined and measured in different ways, and it can be useful to organise evidence within the context of a healthcare system. The advantage of this approach is to contextualise system-level value drivers, their potential interaction, the level of available evidence to quantify value, and evidence gaps.

Our TSV™ framework will provide the context, insight and solutions to help optimize:

  • Stakeholder understanding: Relationships and connections which can change over time
  • Strategy and planning: A framework that delivers access and evidence solutions to support robust strategy and planning, gap analysis and integrated evidence plans
  • Value story: The development and testing of a robust, compelling, fully informed value proposition
  • Value demonstration: Connecting and quantifying muti-stakeholder value perspectives, based on individual
    stakeholder requirements
  • Lifecycle value: A holistic, evolving view of the evidence, access and value drivers, that delivers optimized activities and outcomes at every stage in the product development and commercialisation process

Contact us to find out how our team of system value architects and engineers, can help you understand more about some of healthcare’s wicked problems and unlock a different approach to value demonstration.

Contact our team of value experts

Benefits of a TSV™ approach

  • Better understanding of disease dynamics, healthcare decision consequences, optimisation of evidence and healthcare management
  • Disease and market geography agnostic
  • Connects and quantifies multi-stakeholder value perspectives
  • Identifies evidence gaps and
    value relationships
  • A holistic, dynamic view of evidence and
    value drivers
  • Flexibility to help communicate value effectively and engage with a broader set of stakeholders

More than just HEOR

Global Market Access

We help our clients successfully navigate complex and
ever-changing market access challenges to optimise the value
of their intervention.

Evidence Review & Synthesis

Our in-house team has extensive experience of systematic literature review and all other recognised review methods, employing the appropriate methodology for the research question.


We think outside the box and deliver creative solutions to demonstrate value.


Our fully integrated HTA teams
are experts in developing and critiquing evidence submissions for health technology agencies around the globe.


From basic data visualisation to predictive analysis using AI and machine learning HEOR can transform data into insights.


Effective communication is
essential to convey the value
of healthcare interventions to
relevant stakeholders and ensure optimal access.


If you would like to discuss how TSV™ can address your value demonstration challenges.